Abstract Background Probiotics have gained attention for their potential maintaining gut and immune homeostasis.They have been found to confer protection against pathogen colonization, possess immunomodulatory effects, enhance gut barrier functionality, and mitigate inflammation.However, a thorough understanding of the unique mechanisms of effects
Restless Legs Syndrome (RLS) is a common neurological disorder characterised by an uncontrollable urge to move Fuse Holder the legs.Dopamine agonists are widely used as first or second-line treatments for RLS due to their efficiency in alleviating the symptoms of RLS and improving sleep quality.Whilst efficacious, dopamine agonists can also cause s
Invariant Natural Killer T cells (iNKT) are a versatile lymphocyte subset with important roles in both host defense and immunological tolerance.They express a highly conserved TCR which mediates recognition of the non-polymorphic, lipid-binding molecule CD1d.The structure of human iNKT TCRs is unique in that only one of the six complementarity dete
Two types of variability are discernible in Mirror Covers the ocean: a response to the atmospheric forcing and the so-called internal/intrinsic ocean variability, which is associated with internal instabilities, nonlinearities, and the interactions between processes at different scales.Producing an ensemble of 20 multiyear ocean simulations of the